Azinil (Azithromycin) is indicated inl Acute bacterial exacerbations of chronic obstructive pulmonary disease due to Haemophilus influenzae, Moraxella catarrhalis or Streptococcus pneumoniae.
•Acute bacterial sinusitis due to Haemophilus influenzae, Moraxella catarrhalis or Streptococcus pneumoniae.
•Community-acquired pneumonia due to Chlamydia pneumoniae, Haemophilus influenzae, Mycoplasma pneumonia or Streptococcus pneumoniae.
•Pharyngitis/tonsillitis caused by Streptococcus pyogenes.
•Uncomplicated skin and skin structure infections due to Staphylococcus aureus, Streptococcus pyogenes, or Streptococcus agalactiae.
•Urethritis and cervicitis due to Chlamydia trachomatis or Neisseria gonorrhoeae.
•Genital ulcer disease due to Haemophilus ducreyi (chancroid).
Dosage and administration:
Azinil tablet (Azithromycin) can be taken with or without food.
Azinil-PFS (Azithromycin) should be taken at least 1 hour before or 2 hours after meal.
Adults dosage schedule:
Community-acquired pneumonia Pharyngitis/tonsillitis Skin and skin structure: 500 mg as a single dose on Day 1,followed by 250 mg once daily on Days 2 through 5 td
Acute bacterial exacerbations of chronic obstructive pulmonary disease: 500 mg once daily for 3 days or 500 mg as a single dose on Day 1, followed by 250 mg once daily on Days 2 through 5
Acute bacterial sinusitis: 500 mg once daily for 3 days
Genital ulcer disease: Single 1 gm dose
Non-gonococcal urethritis and cervicitis:Single 1 gm dose
Gonococcal urethritis and cervicitis: Single2 gm dose
Typhoid fever: 500 mg twice daily for 7 days
Children dosage schedule:
The recommended dose of Azinil (Azithromycin) especially for acute otitis media, acute bacterial sinusitis and
community-acquired pneumonia in children over 6 months of age is 10 mg/kg body weight once daily for 3 days or 10
mg/kg on Day 1, followed by 5 mg/kg for next 4 days.
15-25 kg (3-7 years
200 mg (5 ml Azinil-PFS) once daily for 3 days
26-35 kg (8-11 years)
300 mg (7.5 ml Azinil-PFS) once daily for 3 days
36-45 kg (12-14years)
400 mg (10 ml Azinil-PFS) once daily for 3 days
Over 45 kg
Normal adults dosage is recommended
Typhoid fever (3-17 years age) : 20 mg/kg/day for 5 days (maximum dose 1000 mg/day) or 10 mg/kg/day for 7 days
(maximum dose 500 mg/day).
Hepatic impairment : Dose adjustment is not necessary. Renal impairment : Dose adjustment is not necessary with
GFR<80 ml/min but caution should be exercised in severe renal impairment (GFR<10 ml/min)